FIELD: medicine.
SUBSTANCE: invention relates to medicine and pharmacy. Disclosed is the use of thiosulphate to potentiate the anti-pathogen effect of lactobacillus bacteria, selected from Lactobacillus rhamnosus Lcr35 and Lactobacillus crispatus BLL2005, for inhibition of a pathogenic strain Candida albicans, wherein the thiosulphate is present in an amount of at least 100 mg per gram of powder, wherein the powder comprises from 107 to 1010 CFU/g lactobacilli; a composition of the same make-up and use of said composition for inhibiting a pathogenic strain of Candida albicans. Technical result: synergism of the action of the claimed combination against fungi of the genus Candida.
EFFECT: use of the disclosed combination and composition for the treatment of urogenital infections such as vaginosis, candidiasis and urinary tract infections is disclosed.
5 cl, 6 dwg, 8 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| LACTOBACILLUS CRISPATUS STRAIN FOR TREATMENT OR PREVENTION OF SEXUAL AND UROGENITAL INFECTIONS, SUCH AS VAGINOSIS AND CANDIDIASIS, AND USE THEREOF | 2013 |
|
RU2661102C2 |
| COMPOSITIONS FOR TREATING CANDIDIASIS INFECTIONS | 2017 |
|
RU2732244C2 |
| Lactobacillus rhamnosus strain, POSSESSING ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY AGAINST PATHOGENIC AND OPPORTUNISTIC VAGINAL MICROFLORA | 2013 |
|
RU2570622C2 |
| PROBIOTIC STRAINS Lactobacillus AND THEIR CONSORTIUM FOR PROPHYLAXIS AND TREATMENT OF UROGENITAL INFECTIOUS DISEASES OF FEMALES | 2012 |
|
RU2504580C1 |
| Lactobacillus jensenii BACTERIA STRAIN HAVING WIDE SPECTRUM OF ANTAGONIST ACTIVITY AND PROBIOTIC CONSORTIUM OF LACTIC ACID BACILLUS TO PREPARE BACTERIAL FERTILISERS | 2015 |
|
RU2572351C1 |
| STRAIN OF Lactobacillus fermentum Z, USED FOR PRODUCTION OF PROBIOTIC CULTURED MILK FOODS | 2008 |
|
RU2412239C2 |
| CULTURE MEDIUM FOR ISOLATION AND CULTIVATION OF LACTOBACILLUS INERS AND OTHER REPRESENTATIVES OF THE VAGINAL MICROBIOTA | 2022 |
|
RU2794804C1 |
| BACTERIUM STRAINS LACTOBACILLUS RHAMNOSUS 7 DS, WITH A WIDE SPECTRUM OF ANTAGONISTIC ACTIVITY RELATING TO PATHOGENIC AND CONDITIONALLY PATHOGENIC MICROORGANISMS | 2016 |
|
RU2627165C1 |
| Lactobacillus plantarum BACTERIA STRAIN HAVING WIDE RANGE OF ANTAGONISTIC ACTIVITY WITH RESPECT TO PATHOGENS AND OPPORTUNISTIC PATHOGENS | 2012 |
|
RU2482177C1 |
| Lactobacillus rhamnosus BACTERIA STRAIN HAVING WIDE RANGE OF ANTAGONISTIC ACTIVITY WITH RESPECT TO PATHOGENS AND OPPORTUNISTIC PATHOGENS | 2012 |
|
RU2482176C1 |
