MEANS INCLUDING FAT EMULSION (VARIANTS), ITS USE AND METHOD OF CREATING REVERSIBLE PHARMACOLOGICALLY INDUCED HYPOMETABOLISM AND HYPOTHERMIA Russian patent published in 2018 - IPC A61K31/138 A61K31/475 A61K31/4045 A61K31/513 A61K31/5415 A61K31/55 A61K33/06 A61K47/04 A61K47/44 A61K9/08 A61K9/10 A61P43/00 

Abstract RU 2668374 C1

FIELD: pharmaceuticals.

SUBSTANCE: claimed group of inventions relates to pharmaceutical composition intended to provide an agent for induced hypometabolism and hypothermia in mammals. Pharmaceutical composition includes the beta-blocker propranolol, sympatholytik reserpine, antianginal drug ivabradine antihistamine drug diphenhydramine, serotonin hydrochloride, neuroleptic agent with hypothermic effect of pericyazine, antithyroid agent propitsil, magnesium sulfate and pharmaceutically acceptable solvent. Agent further comprises a carrier, a fat emulsion, which is selected from the group consisting of lipofundin, smo flipid, interlipid. In another embodiment of the invention, a fat emulsion saturated with an inert gas is used, which is selected from the group consisting of xenon, helium, hexafluoride.

EFFECT: invention provides use of a new agent in emergency medicine.

9 cl, 3 dwg, 3 ex

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RU 2 668 374 C1

Authors

Biryukov Sergej Vladimirovich

Zakharova Nadezhda Mikhajlovna

Komelina Natalya Pavlovna

Semenov Vitalij Semenovich

Semenov Ivan Vitalevich

Tarakhovskij Yurij Semenovich

Fadeeva Irina Sergeevna

Khrenov Maksim Olegovich

Dates

2018-09-28Published

2017-08-11Filed