METHOD OF INHIBITING TUMOUR GROWTH IN MAMMAL Russian patent published in 2020 - IPC A61K9/107 A61K31/135 A61K31/137 A61K31/138 A61K31/275 A61K31/475 A61K31/505 A61K31/5517 A61P43/00 

Abstract RU 2713153 C1

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine and can be used for tumour growth inhibition in a mammal. That is ensured by using agent containing 20 % fat lipofundin emulsion, xenon saturated with inert gas, propranolol beta blocker, reserpine sympatholytic, ivabradine antianginal preparation, an antihistamine preparation of diphenhydramine, a neuroleptic preparation with hypothermic action of Periciazine, serotoninergic agent serotonin hydrochloride, an antithyroid agent Propycil, magnesium sulphate and a pharmaceutically acceptable solvent, and a second preparation which contains 20 % lipofundin fat emulsion, xenon-saturated inert gas, wherein 1 ml of 20 % fat lipofundin emulsion contains 0.54 ml to 2.2 ml of xenon at saturation under pressure of 2 atm. Agent is injected into a mammal, after which the mammal is exposed to additional hypoxia by reducing oxygen in the external medium to level of 5 % and maintained in these conditions for 1.5–3 hours.

EFFECT: group of inventions provides intensified therapeutic effect ensured by synergetic action of said agents and subsequent use of external hypoxia on inhibition of tumor growth and regression at initial stage of growth.

7 cl, 2 dwg, 1 ex

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RU 2 713 153 C1

Authors

Zakharova Nadezhda Mikhajlovna

Glushkova Olga Valentinovna

Komelina Natalya Pavlovna

Fadeeva Irina Sergeevna

Biryukov Sergej Vladimirovich

Dates

2020-02-04Published

2018-10-11Filed