FIELD: medicine; chemistry.
SUBSTANCE: invention relates to use of duocarmicin conjugates of antibody-drug (ADC) of formula (II) for treating human solid tumours expressing HER2, wherein said human solid tumour expressing HER2 is HER2 IHC 2+ or 1.
EFFECT: advantage of conjugates of the declared invention consists in possibility of their application for treatment of thrice negative breast cancer (TNBC).
8 cl, 12 dwg, 1 ex
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Authors
Dates
2019-05-29—Published
2015-01-09—Filed