FIELD: pharmaceuticals.
SUBSTANCE: invention relates to duocarmycin-containing antibody-drug conjugates (ADCs) for application in treatment of HER2-expressing human solid tumours, wherein the HER2-expressing human solid tumour constitutes HER2 IHC 3+ bladder cancer, the bladder cancer is HER2 FISH-negative.
EFFECT: creation of ADCs applicable in treatment of cancer.
2 cl, 12 dwg, 1 ex
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