FIELD: medicine.
SUBSTANCE: invention relates to a method for the treatment of malignant tumor expressing ErbB2, including the administration of a therapeutic combination, in the form of a combined composition or alternately, to a mammal, where the therapeutic combination contains trastuzumab-MCC-DM1 and docetaxel, where the administration of the therapeutic combination leads to an additive effect compared to the administration of trastuzumab-MCC-DM1 or docetaxel in the form of separate remedies, where the amount of trastuzumab-MCC-DM1 is from 0.3 to 15 mg/kg, and where the amount of docetaxel is about 30 mg/kg.
EFFECT: obtaining combination of an antibody-drug conjugate and chemotherapeutic means.
10 cl, 37 dwg, 21 tbl, 5 ex
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Authors
Dates
2022-10-07—Published
2018-10-12—Filed