VISUAL GUIDANCE FOR RADIATION THERAPY Russian patent published in 2018 - IPC A61N5/10 A61B6/00 A61B8/00 G06T7/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. Group of inventions is represented by a computerized method of controlling an adaptive system for carrying out radiation therapy and an adaptive system for conducting radiation therapy. Adaptive system contains a generator for therapy, a controller system, and a visualizing input device. Interfractional volumetric image is obtained containing a time-varying target locus. Interfractional three-dimensional image is obtained in the first period of time. At least two intrafraction imaging slices are obtained containing different portions of the target locus. First intrafractive imaging slice is obtained in the second time period. Second intrafractive imaging slice is obtained in the third time period. These at least two intrafraction imaging slices are obtained simultaneously in the same session of fractional radiation therapy, as well as the conducted radiation therapy, and they are in different planes of visualization having different orientations. Spatial alignment of the target locus portion from the first intrafraction imaging slice and the target locus portion from the second intrafraction imaging slice is performed, including translational movement of a portion of the target locus in a second intrafraction imaging slice to align a portion of the target locus in the second intrafraction imaging slice with a portion of the target locus in the first intrafraction imaging slice. Difference is determined between the location of the target locus indicated by spatially aligned information, and location of the target locus indicated by the interfractional volumetric image. Adjusted treatment protocol is generated to control the delivery of the therapeutic beam based on the established difference.

EFFECT: group of inventions allows to carry out radiation therapy, to adapt the plan of radiotherapeutic treatment with the purpose of introducing correction for changes in the position of the target tumor in the process of radiation therapy by obtaining an interfractional volumetric image and, at least, two intrafractional imaging slices, their spatial juxtaposition, and the determination of the differences between the location of the target locus.

25 cl, 13 dwg