FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology, specifically to therapeutic peptides from TLT-1 (Trem-like transcript-1), and can be used in medicine.
EFFECT: obtained TLT-1 peptide fragments are effective in the treatment of cardiovascular diseases selected from the group consisting of myocardial or cerebral infarction, acute myocardial infarction, coronary heart disease, stroke, aneurysm, stable angina or angina pectoris, cardiomyopathy, hypertensive cardiopathy, heart failure (chronic or acute), pulmonary heart disease, cardiac arrhythmias, inflammatory heart diseases such as endocarditis, myocarditis, peripheral arterial disease, SIRS (systemic inflammatory response syndrome)-associated myocardial and vascular dysfunction, atherosclerosis.
10 cl, 22 dwg, 5 tbl, 15 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS FOR IDENTIFYING AND PREDICTING RISK OF CARDIOVASCULAR EVENT OR DISEASE OR FATAL OUTCOME, METHODS FOR ASSESSING SEVERITY AND MONITORING OF CARDIOVASCULAR EVENT OR DISEASE, METHOD FOR MONITORING EFFECTIVENESS OF THERAPY | 2014 |
|
RU2721690C2 |
| APOPTOSIS INHIBITORS AND USE THEREOF | 2011 |
|
RU2582247C2 |
| NEW METHOD OF TREATMENT OF MYOCARDIAL INFARCTION WITH APPLICATION OF FRAGMENT HMGB1 | 2013 |
|
RU2647467C2 |
| IMMUNOTHERAPEUTIC TREATMENT | 2006 |
|
RU2454428C2 |
| CELL-BASED THERAPY OF ISCHEMIC TISSUE | 2009 |
|
RU2535966C2 |
| THERAPEUTIC AGENT FOR THE TREATMENT OF CARDIOMYOPATHY, PREVIOUS MYOCARDIAL INFARCTION AND CHRONIC HEART FAILURE | 2018 |
|
RU2795320C2 |
| PHARMACEUTICAL PREPARATION | 2009 |
|
RU2542512C2 |
| METHOD FOR OBTAINING UP-REGULATING PD-L1 EXPRESSION, POLYPEPTIDES, A CONJUGATE, A FUSED POLYPEPTIDE, A COMPOSITION AND A COMBINATION TO PROVIDE UP-REGULATING EXPRESSION OF PD-L1 | 2016 |
|
RU2734169C2 |
| MIMETIC PEPTIDES | 2013 |
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RU2662973C2 |
| APTAMERS SPECIFIC FOR TLR-4, AND USE THEREOF | 2015 |
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RU2709718C2 |
