5-HYDROXY-4-(TRIFLUOROMETHYL)PYRAZOLOPYRIDINE DERIVATIVE Russian patent published in 2018 - IPC C07D471/04 A61K31/4545 A61K31/497 A61K31/501 A61K31/506 A61P13/12 A61P3/06 A61P9/04 A61P9/10 A61P43/00 

Abstract RU 2673810 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a compound represented by general formula (I) or a pharmacologically acceptable salt thereof, in which the radicals and symbols have the values given in the claims.

.

EFFECT: present compound has an excellent LCAT-activating effect and is useful as an active ingredient of a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disorder, and angiogenesis restenosis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular diseases (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia or kidney disease, in particular, as an anti-arteriosclerotic agent.

41 cl, 1 dwg, 2 tbl, 41 ex

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RU 2 673 810 C1

Authors

Kobayasi Khideki

Arai Masami

Kaneko Tosio

Terasaka Naoki

Dates

2018-11-30Published

2014-12-12Filed