FIELD: chemistry.
SUBSTANCE: invention relates to a compound represented by general formula (I) or a pharmacologically acceptable salt thereof, in which the radicals and symbols have the values given in the claims.
.
EFFECT: present compound has an excellent LCAT-activating effect and is useful as an active ingredient of a therapeutic or prophylactic agent for arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disorder, and angiogenesis restenosis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular diseases (including diabetic vascular complications), dyslipidemia, hypo-HDL-cholesterolemia, hyper-LDL-cholesterolemia or kidney disease, in particular, as an anti-arteriosclerotic agent.
41 cl, 1 dwg, 2 tbl, 41 ex
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Authors
Dates
2018-11-30—Published
2014-12-12—Filed