METHOD FOR SYNTHESIS OF N-(PHOSPHONOMETHYL)GLYCINE Russian patent published in 2018 - IPC C07F9/38 A01N57/20 

FIELD: chemistry.

SUBSTANCE: invention relates to a method for the synthesis of N-(phosphonomethyl)glycine or a salt thereof – highly effective phytotoxic agent. Method includes the following steps: a) forming a reaction mixture containing an acid catalyst, N,N'-bis(carboxymethyl)-2,5-diketopiperazine and a compound containing one or more P-O-P anhydride moieties, where said moieties contain one P atom in the oxidation state (+III) and another P atom in the oxidation state (+III) or (+V), to form N,N'-bis(phosphonomethyl)-2,5-diketopiperazine, wherein the compound containing one or more P-O-P anhydride moieties, where said moieties contain one P atom in oxidation state (+III) and another P atom in oxidation state (+III) or (+V), is selected from tetraphosphorus hexaoxide, P₄O₇, P₄O₈, P₄O₉, tetraphosphorus decaoxide, tetraethyl pyrophosphite, dimethyl phosphite, and combinations thereof; and b) hydrolysis of the reaction mixture to form N-(phosphonomethyl)glycine or a salt thereof. If hydrolysis is carried out under basic conditions, the salt contains a carboxylate and/or phosphonate anion of N-(phosphonomethyl)glycine and an alkali metal, alkaline earth metal or ammonium cation; if hydrolysis is carried out under acidic conditions, the salt contains the ammonium cation of N-(phosphonomethyl)glycine and the anion, which passes from the acid used for the hydrolysis; and/or the cation of the salt of N-(phosphonomethyl)glycine is selected from the group consisting of ammonium, isopropylammonium, ethanolammonium, dimethylammonium, trimethylsulphonium, alkali or alkali-earth metal.

EFFECT: disclosed method enables to obtain the desired product using high-performance and environmentally friendly technology.

28 cl, 1 tbl, 1 ex