FIELD: medicine, chemical-technological industry.
SUBSTANCE: the present innovation deals with applying the antagonist of glucocorticoid receptor (11β,17β)-11-(1,3-benzodioxol-5-il)-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-on (Org 34517) for obtaining a medicinal preparation in the form applied for peroral intake for treating patients suffering with considerable depressive disorder and, also, the corresponding method of therapy. The suggested Org 34517 initiated quicker onset of antidepressive action against paroxetin.
EFFECT: higher efficiency of application.
6 cl, 3 dwg, 1 ex
Title | Year | Author | Number |
---|---|---|---|
DERIVATIVE OF 11-(PHENYL-SUBSTITUTED)-ESTRA-4,9-DIENE, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION | 1996 |
|
RU2135514C1 |
DERIVATIVES OF 16-HYDROXY-11-(SUBSTITUTED PHENYL)-ESTRA-4,9-DIENE, COMPOUND, PHARMACEUTICAL COMPOSITION | 1998 |
|
RU2187510C2 |
DERIVATIVES OF 11,21-BISPHENYL-19-NORPREGNANE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING | 1995 |
|
RU2152952C2 |
DERIVATIVES OF 11β-BENZALDOXIME-ESTRA-4,9-DIENE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION | 1994 |
|
RU2137777C1 |
DERIVATIVES OF 11β--BENZALDOXIME-ESTRA-4,9-DIENE, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION | 1994 |
|
RU2130944C1 |
HORMONAL OR ANTI-HORMONAL STEROID COMPOUNDS, METHODS FOR THERAPEUTIC EFFECT, METHOD FOR PREPARING COMPOUNDS | 1999 |
|
RU2238943C2 |
USE OF COMPETITIVE PROGESTERONE ANTAGONISTS FOR CONTRACEPTION, NEW COMPOUNDS OF ORDER OF COMPETITIVE PROGESTERONE ANTAGONISTS | 1993 |
|
RU2137476C1 |
ANTIGLUCOCORTICOID DRUG | 1996 |
|
RU2125446C1 |
17 β -OXYESTRATRIENES | 2002 |
|
RU2339643C2 |
PROGESTERONE ANTAGONISTS | 2012 |
|
RU2608521C2 |
Authors
Dates
2007-07-10—Published
2002-10-21—Filed