METHOD OF INHIBITING KAPPA NUCLEAR FACTOR WITH THE USE OF POTASSIUM 5-HYDROXYNICOTINATE IN A CELL CULTURE Russian patent published in 2018 - IPC G01N33/48 

Abstract RU 2675693 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine and relates to a method of inhibiting the nuclear factor kappa B in a cell culture, including the addition of bacterial lipopolysaccharide at a concentration of 1 mcg/ml to the freshly isolated by the standard method on a ficoll density gradient to mononuclear blood cells of Wistar rats, then adding potassium 5-hydroxynicotinate dissolved in phosphate-buffered saline to a final concentration of 35 mcg/ml to this mixture.

EFFECT: invention provides effective inhibition of the nuclear factor kappa B.

1 cl, 1 tbl, 1 ex

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RU 2 675 693 C1

Authors

Danilenko Lyudmila Mikhajlovna

Pokrovskij Mikhail Vladimirovich

Timokhina Alena Sergeevna

Kesarev Oleg Georgievich

Peresypkina Anna Aleksandrovna

Martynov Mikhail Alekseevich

Kostina Darya Aleksandrovna

Skachilova Sofiya Yakovlevna

Zhilinkova Lyudmila Anatolevna

Burda Yurij Evgenevich

Linnik Marina Sergeevna

Yakushev Vladimir Ivanovich

Dates

2018-12-24Published

2017-11-16Filed