FIELD: medicine.
SUBSTANCE: invention relates to medicine and relates to a method of inhibiting the nuclear factor kappa B in a cell culture, including the addition of bacterial lipopolysaccharide at a concentration of 1 mcg/ml to the freshly isolated by the standard method on a ficoll density gradient to mononuclear blood cells of Wistar rats, then adding potassium 5-hydroxynicotinate dissolved in phosphate-buffered saline to a final concentration of 35 mcg/ml to this mixture.
EFFECT: invention provides effective inhibition of the nuclear factor kappa B.
1 cl, 1 tbl, 1 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR INHIBITING NUCLEAR FACTOR KAPPA B WITH USE OF 5-HYDROXYNICOTINATE 3-(2,2,2-TRIMETHYLHYDRAZINIUM) POTASSIUM PROPIONATE IN CELL CULTURE | 2017 |
|
RU2674443C1 |
| METHOD FOR INHIBITING NUCLEAR KAPPA B FACTOR WITH USING 2-ETHYL-6-METHYL-3-HYDROXIPIRIDINIUM L-2,6-DIAMINOHEXANOATE IN CULTURE OF CELLS | 2017 |
|
RU2669348C1 |
| USE OF ARSENIC COMPOUNDS TO TREAT TISSUE OR ORGAN REJECTION | 2013 |
|
RU2665362C2 |
| USE OF ARSENIC COMPOUNDS FOR PAIN MANAGEMENT AND INFLAMMATION TREATMENT | 2008 |
|
RU2630574C2 |
| EMPLOYMENT OF (R)-ARYLPROPIONIC ACIDS TO PREPARE DRUGS FOR TREATMENT OF HUMANS AND ANIMALS LIABLE TO BE THERAPEUTICALLY AFFECTED VIA NF-κB ACTIVATION INHIBITION | 2000 |
|
RU2250103C2 |
| METHOD OF LOADING DENDRITIC CELLS WITH ANTIGEN OF INFECTIOUS ORIGIN Opistorchis felineus | 2011 |
|
RU2486238C1 |
| SUBSTANCE POSSESSING ANTI-INFLAMMATORY, IMMUNOMODULATING AND WOUND-HEALING ACTIVITY | 2005 |
|
RU2300384C2 |
| METHOD FOR EARLY PREDICTION OF MISCARRIAGE ASSOCIATED WITH REACTIVATION OF CYTOMEGALOVIRUS INFECTION | 2022 |
|
RU2787451C1 |
| NEW COMPOUND ISOLATED FROM PSEUDOLYSIMACHION ROTUNDUM VAR. SUBINTEGRUM, WITH A HIGH CONTENT OF ACTIVE INGREDIENT, COMPOSITION CONTAINING SAID COMPOUND FOR PREVENTING OR TREATING ALLERGIC DISEASE, INFLAMMATORY DISEASE, ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND USE THEREOF | 2015 |
|
RU2685732C2 |
| DRUG WITH ANTI-INFLAMMATORY ACTIVITY | 2016 |
|
RU2617123C1 |
