HIGH DOSE LEVODOPA CAPSULES FOR PULMONARY USE Russian patent published in 2018 - IPC A61K9/12 A61K31/137 A61K9/16 A61P25/16 

Abstract RU 2676093 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. Capsule containing an inhalable powder composition containing 75 wt. % or more of levodopa, dipalmitoylphosphatidylcholine (DPPC) and salt. Powder is characterised by a working density of less than 100 g/l. Described is a capsule containing an inhalable powder composition containing 75 wt. % or more of levodopa, dipalmitoylphosphatidylcholine (DPPC) and salt, the powder is characterised by a working density of less than about 100 g/l, and wherein the capsule shell contains hydroxypropyl methylcellulose (HPMC) and titanium dioxide.

EFFECT: capsule provides the release of a larger amount of powder compared to the amount of powder released from capsules that do not contain titanium dioxide as capsule material.

18 cl, 6 dwg, 26 tbl, 4 ex

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RU 2 676 093 C2

Authors

Ki Kevin D.

Penako Ernest D.

Kamerkar Abkhidzhit

Lipp Majkl M.

Batiki Richard P.

Dates

2018-12-26Published

2013-11-08Filed