THERAPEUTIC PEPTIDES Russian patent published in 2019 - IPC C07K7/02 C07K5/23 C07D279/14 C07D295/192 C07D237/20 C07D295/185 A61K38/08 A61P35/00 

Abstract RU 2676713 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method for treating tumor cells or prophylaxis, or suppressing the growth, spread, or metastasis of a tumor by administering to a patient a peptide, peptidomimetic or an amino acid derivative having a net positive charge of at least +2 at pH 7.0 and containing disubstituted β-amino acid, each of the substituting groups in β-amino acid, which may be the same or different, includes at least 7 non-hydrogen atoms, is lipophilic and includes at least one cyclic group, moreover, one or more cyclic groups in the substituting group may be linked or fused with one or more cyclic groups in another substituting group, and when cyclic groups are fused in this way, the combined total number of non-hydrogen atoms for these two substituting groups is at least 12.

EFFECT: therapeutic peptides are proposed.

10 cl, 4 dwg, 10 tbl, 4 ex

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RU 2 676 713 C2

Authors

Strem Morten

Khansen Terkel

Khavelkova Martina

Terfoss Veronika

Dates

2019-01-10Published

2010-11-02Filed