FIELD: medicine.
SUBSTANCE: invention refers to medicine and biotechnology and concerns an antimicrobial peptide compound. Substance of the invention consists in use of an amino acid compound containing the sequence IGKEFKRIVERIKRFLRELVRPLR for preparing a drug for fungal or bacterial infection in a mammal. Besides said compound exhibits sensitivity to toxins, and especially to bacterial toxins, such as lipopolysaccharide or lipoteichoic acid.
EFFECT: extended field of use in comparison with antibiotics.
22 cl, 9 ex, 4 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| PEPTIDE INHIBITORS OF TOXINS DERIVATIVES OF LL-37 | 2004 |
|
RU2346950C2 |
| ANTIMICROBIAL PEPTIDE | 2014 |
|
RU2695455C2 |
| ANTIMICROBIAL PEPTIDE AND USE THEREOF | 2014 |
|
RU2699712C1 |
| PEPTIDES AND USE THEREOF | 2011 |
|
RU2590706C2 |
| IDENTIFICATION OF LYSINES AND THEIR DERIVATIVES WITH ANTIBACTERIAL ACTIVITY AGAINST PSEUDOMONAS AERUGINOSA | 2018 |
|
RU2807688C2 |
| ANTIBIOTIC PEPTIDES | 2008 |
|
RU2472805C2 |
| PEPTIDES, DETACHED FROM HUMAN LACTOFERRIN, AND USE THEREOF | 2012 |
|
RU2593757C2 |
| BACTERIOPHAGE-DERIVED ANTIMICROBIAL POLYPEPTIDES AND THEIR USE AGAINST GRAM-NEGATIVE BACTERIA | 2019 |
|
RU2804774C2 |
| COMPOSITION CONTAINING LACTIC ACID AND LACTOFERRIN | 2005 |
|
RU2398575C2 |
| CYCLIC ANTIMICROBIAL PEPTIDES | 2006 |
|
RU2463308C2 |
