FIELD: medicine.
SUBSTANCE: invention relates to medicine and pharmaceuticals and relates to the method for preparing an injectable form of the chondroitin sulfate preparation. Method comprises the sequential dissolution of sodium disulfite, chondroitin sodium sulfate, benzyl alcohol in injectable water, followed by adjusting, if necessary, the pH of the solution to 6.0–7.5, however, the entire process of dissolving the ingredients is carried out under nitrogen protection. Finished solution of the drug is filtered using sterilizing filtration, poured into the ampoules and the ampoules are sealed in the flow of nitrogen. Method provides for minimal risks of degradation of molecular structure and changes in the molecular weight range of chondroitin sulfate, as well as for minimal risks of initial contamination of the solution and the accumulation of backendotoxins. Method is quick and easy to implement. Method is also characterized by the elimination of the appearance of pink staining solution and the preservation of the required values of the quantitative content of chondroitin sulfate, color and pH of the solution for more than 2 years of storage.
EFFECT: preparation is a stimulator of tissue repair.
5 cl, 1 tbl, 1 ex
