BENZISOXAZOLE SALT DERIVATIVE Russian patent published in 2019 - IPC C07D413/14 A61K31/454 A61P1/00 A61P9/00 A61P25/00 

Abstract RU 2679619 C2

FIELD: chemistry.

SUBSTANCE: invention relates to new salts 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazole-3-yl]oxy}methyl)piperidin-1-yl]methyl}tetrahydro2H-pyran-4-carboxylic acid, as well as to methods for producing such salt forms, pharmaceutical compositions containing them, their use for treating disease states mediated by 5-HT4 receptor activity.

EFFECT: technical result: new salt forms (HCl-salt, HBr-salt, p-toluenesulfonate salt and ethanedisulfonate salt) are obtained, possessing better stability and low hygroscopicity.

20 cl, 10 dwg, 2 tbl, 2 ex

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RU 2 679 619 C2

Authors

Numata, Toyoharu

Sudo, Masaki

Sun, Xufeng

Dates

2019-02-12Published

2015-05-20Filed