FIELD: chemistry.
SUBSTANCE: invention relates to specific compounds that are pyrazole derivatives of curcumin and have structural formulas executed in the claims. These compounds inhibit the aggregation of tau protein and β-amyloid protein, and also they inhibit β-secretase.
EFFECT: they can be used in treatment of Alzheimer's disease and other diseases mediated by these proteins.
4 cl, 41 tbl, 59 ex
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