FIELD: chemistry.
SUBSTANCE: invention relates to the agent strongly inhibiting thrombocyte aggregation, it doesn't inhibit COX-1 or COX-2. The invention offers the compounds of formula (I) 
or their pharmaceutically acceptable salts, where residuals and groups in the specified structure of the compounds have the values denoted in the formula of the invention. The pharmaceuticals containing any of the compounds of formula (I) or their pharmaceutically acceptable salts, and phylactic and/or therapeutic agents for coronary heart disease, which contain any of the compounds of formula (I) or their pharmaceutically acceptable salts are suggested. Moreover, application of the compounds and their pharmaceutically acceptable salts for preparation of the medicine having anti-thrombotic potency, and method of the treatment of coronary heart disease are suggested.
EFFECT: production of the medicines having anti-thrombotic potency on basis of pyrazole.
12 cl, 1 tbl, 171 ex
| Title | Year | Author | Number |
|---|---|---|---|
| INHIBITOR COMPOUNDS | 2013 |
|
RU2673079C2 |
| SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS, METHODS OF PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE AGENT | 2014 |
|
RU2654483C2 |
| PYRAZOLO[1,5-A]PYRIDINES AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | 2002 |
|
RU2308457C2 |
| GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS ACTIVE INGREDIENT | 2008 |
|
RU2450001C2 |
| AMIDOCARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHOD OF REDUCING GLUCOSE IN BLOOD | 1998 |
|
RU2176999C2 |
| HEXACYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THEREOF AND THEIR USING AS ANTITUMOR AGENTS, METHOD FOR PREPARING HEXACYCLIC COMPOUNDS | 2002 |
|
RU2299212C2 |
| DIAMINE DERIVATIVES | 2003 |
|
RU2333203C2 |
| PYRIDOXAZINONE DERIVATIVES AS TNAP INHIBITORS | 2016 |
|
RU2715704C2 |
| PYRIDYL DIMETHYLSULPHONIC DERIVATIVE | 2006 |
|
RU2404968C2 |
| 2-PYRIDONE DERIVATIVES | 2010 |
|
RU2551847C2 |
