METHOD OF RADIONUCLIDAL DIAGNOSTICS OF BREAST CANCER Russian patent published in 2019 - IPC A61K51/04 A61K103/10 

Abstract RU 2682880 C1

FIELD: medicine.

SUBSTANCE: invention relates to oncology, and is a method for the radionuclide diagnosis of breast cancer, including intravenous administration of a radiopharmaceutical preparation (RP) and subsequent radionuclide scanning, characterized in that a radiopharmaceutical preparation based on labelled 99mTc of glucose in the form of a solution for intravenous injection is injected in the composition: 1-thio-D-glucose sodium salt hydrate 0.625 mg, tin 2-water dichloride 0.044–0.052 mg, ascorbic acid 0.125 mg, sodium chloride 8.0–10.0 mg, water for injection up to 1 ml, in a dose of 500 MBq and after 40 min after drug administration, single-photon emission computed tomography is performed on a two-detector gamma camera, the obtained images are subjected to postprocessing processing using a specialized programs pack and during the visualization of asymmetric areas of hyperfixation of radiopharmaceuticals in the breast tissue, more than 2 times the accumulation in the symmetric area, a malignant tumor is diagnosed.

EFFECT: invention provides improved accuracy and informativeness for diagnosing breast cancer.

1 cl, 1 dwg, 1 tbl

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RU 2 682 880 C1

Authors

Chernov Vladimir Ivanovich

Zelchan Roman Vladimirovich

Medvedeva Anna Aleksandrovna

Bragina Olga Dmitrievna

Sinilkin Ivan Gennadevich

Skuridin Viktor Sergeevich

Stasyuk Elena Sergeevna

Tagirova Ekaterina Alekseevna

Slonimskaya Elena Mikhajlovna

Doroshenko Artem Vasilevich

Vernadskij Roman Yurevich

Dudnikova Ekaterina Aleksandrovna

Dates

2019-03-22Published

2017-10-02Filed