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2 687 001

(13)

(51)

IPC

C07K14/01(2006-01-01)

A61K39/12(2006-01-01)

A61P31/20(2006-01-01)

C12N15/34(2006-01-01)

G01N33/53(2006-01-01)

(21) (22)

Application

2015135619, 2014-01-23

(24)

Start date

2014-01-23

(22)

Actual filing date

2014-01-23

(45)

Published

2019-05-06

(72)

Inventor

Di-Almeida Marsiya-RozheriyaZhunior Abelardu-SilvaFettu Zhuliana-Lopesh-RanzhelBressan Gustvu-KostaSalgado Rafael-LokatelliOnufre Tyagu-SozaFaustu Mariana-KoshtaVidigal Pedru-Markush-PerejraKalksh Stefani-PatareliKrishpim Zhuziselli-SozaAmazilish-Silva-Lejte RobertaAndrade-Tejshejra Zhakson-DiFyalu-Gonzaga NatalyaZhakel-Zilsh TyaguLinu-Di-Soza LuishDa-Krush-Soza Amanda-MartinshDi-Moraish-Montejru Antonyu

(73)

Holder

Fundasan Di-Amparo A Peskiza Du-Estadu Di-Minas Zherajs-FapemigUniversidadi Federal Di-Visoza

RECOMBINANT PORCINE CIRCOVIRUSES 2 (PCV-2) ANTIGENS FOR VACCINE COMPOSITIONS, DIAGNOSTIC KIT AND USE THEREOF Russian patent published in 2019 - IPC C07K14/01 A61K39/12 A61P31/20 C12N15/34 G01N33/53

Abstract RU 2687001 C2

FIELD: biotechnology.

SUBSTANCE: invention describes production of recombinant antigen of porcine circovirus virus 2 (PCV-2) viral capsid and its modification by means of expression in prokaryotic system, purification in monomer form, virus-like particle (VLP) release and use thereof in vaccine compositions, diagnostic kits and a system for quantitative evaluation of PCV-2 antigen in batches of vaccines by analysis with the help of (antigen)capturing ELISA. Antigens and compositions of vaccines can be used in animal immunization programs for controlling PCV-2-associated diseases in conventional pigs breeding systems, and they are alternatives to commercially available vaccines.

EFFECT: kit for ELISA can be used to assess the quality of commercially available and / or experimental PCV-2 vaccines.

11 cl, 16 dwg, 2 ex

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RU 2 687 001 C2

Authors

Di-Almeida Marsiya-Rozheriya

Zhunior Abelardu-Silva

Fettu Zhuliana-Lopesh-Ranzhel

Bressan Gustvu-Kosta

Salgado Rafael-Lokatelli

Onufre Tyagu-Soza

Faustu Mariana-Koshta

Vidigal Pedru-Markush-Perejra

Kalksh Stefani-Patareli

Krishpim Zhuziselli-Soza

Amazilish-Silva-Lejte Roberta

Andrade-Tejshejra Zhakson-Di

Fyalu-Gonzaga Natalya

Zhakel-Zilsh Tyagu

Linu-Di-Soza Luish

Da-Krush-Soza Amanda-Martinsh

Di-Moraish-Montejru Antonyu

Dates

2019-05-06—Published

2014-01-23—Filed