FIELD: medicine.
SUBSTANCE: invention relates to the field of medicine and is intended to assess the effectiveness of the treatment of leprosy based on the identification of viable Mycobacterium leprae. DNA/RNA is isolated from skin biopsies and scarifiers. Reaction of RT-PCR is carried out in real time. With a decrease in the bacterioscopic index (BIN) and the percentage of positive samples obtained 6 and 9 months after the start of treatment, the effectiveness of anti-mycobacterial therapy is determined.
EFFECT: invention provides improved method accuracy.
1 cl, 4 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| METHOD FOR PREDICTION OF RECURRENCE RISK IN LEPROSY PATIENTS | 2008 |
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|
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| METHOD OF ESTIMATION OF LEPROSY RELAPSE RISK GROUP | 1993 |
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| METHOD OF LEPROSY DIAGNOSIS | 1996 |
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| METHOD OF IDENTIFICATION OF MYCOBACTERIUM LEPRAE IN PATIENTS WITH DISEASE REGRESSION | 1997 |
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| METHOD FOR INCREASE OF REAL TIME POLYMERASE CHAIN REACTION SENSITIVITY IN DETECTION OF PATHOGENIC BACTERIA DNA | 2016 |
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| METHOD FOR DIAGNOSING LEPROSIS | 2000 |
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| METHOD OF MONITORING EFFECTIVENESS OF TREATING CHRONIC MYCOBACTERIOSIS | 2007 |
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| LEPROSY MICROBACTERIA STORAGE METHOD | 2007 |
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RU2360959C1 |
