FIELD: chemistry.
SUBSTANCE: invention relates to low-molecular non-peptide compounds of formula 1, where values of R1-R5, Z, ring A, ring B are specified in the patent claim, as well as methods and compositions for treating angiotensin-associated diseases and disorders.
.
EFFECT: compounds according to the present invention are suitable for treating metabolic diseases and disorders, such as diabetes mellitus, diabetes-related cardiovascular disorders associated with skin ulceration diabetes, diabetes-related hypertension and diabetes-related eye diseases.
29 cl, 10 dwg, 15 ex
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