METHOD OF PREVENTION AND TREATMENT OF LIVER DISEASE WITH APPLICATION OF RECEPTOR A ANTAGONISTS Russian patent published in 2012 - IPC A61K31/522 A61P1/16

Abstract RU 2457842 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to field of medicine. Method of treatment and prevention of liver fibrosis includes peroral introduction to mammal of therapeutically efficient amount of antagonist of adenosine receptor A_2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl)-1,3,7-trihydropurine-2,6-dione. Method of reducing hepatotoxic side effects of chemical therapy or radiotherapy includes peroral introduction to mammal who underwent such treatment of therapeutically efficient amount of antagonist of adenosine receptor A_2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl) -1,3,7-trihydropurine-2,6-dione.

EFFECT: application of claimed group of inventions is efficient for prevention and treatment of liver diseases.

6 dwg, 21 ex

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RU 2 457 842 C2

Authors

Tszen Dehvan'

Chzhun Khunjan'

Belardinelli Luis

Dates

2012-08-10—Published

2007-03-16—Filed