FIELD: chemistry.
SUBSTANCE: present invention relates to compounds of formula (I), where R1-R8 such as defined herein, or pharmaceutically acceptable salts thereof, as inhibitors of ubiquitin-C-terminal hydrolase L1 (UCHL1).
EFFECT: present invention also relates to use of compounds for treating cancer, which is associated with UCHL1 activity and other conditions associated with UCHL1.
18 cl, 2 dwg, 15 tbl, 266 ex
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Authors
Dates
2019-06-13—Published
2015-09-22—Filed