METHODS AND COMPOSITIONS FOR TREATING DRY EYE DISEASE AND OTHER EYE DISEASES Russian patent published in 2019 - IPC A61K9/08 A61K31/498 A61P27/02 

FIELD: medicine.

SUBSTANCE: group of inventions relates to ophthalmology, and is intended for treating a patient suffering dry eye syndrome. For treating a patient suffering dry eye syndrome, as well as for treating meibomian glandular dysfunction (MGD) in a subject, an ophthalmic pharmaceutical formulation comprising a therapeutically effective amount of an alpha-2 adrenergic agonist is used on the subject's eye. Said alpha-2 adrenergic agonist is brimonidine or a pharmaceutically acceptable salt thereof. Therapeutically effective amount is amount of 0.15–0.07 wt. %. Also provided is an ophthalmic composition for topical use, comprising brimonidine or a pharmaceutically acceptable salt thereof and mineral oil or Vaselin jelly.

EFFECT: group of inventions provides effective treatment of a patient suffering dry eye syndrome.

26 cl, 5 ex