INTRANASAL DEXMEDETOMIDINE COMPOSITIONS AND METHODS OF USE THEREOF Russian patent published in 2019 - IPC A61K9/12 A61K31/4174 A61P25/06 

FIELD: medicine.

SUBSTANCE: invention refers to therapy and neurology, and can be used for treating pain in an adult. For this purpose, intramuscularly one nostril is administered a pharmaceutical composition containing dexmedetomidine or its pharmaceutically acceptable salt in dose 35 ± 10 % mcg, 40 ± 10 % mcg, 45 ± 10 % mcg, 50 ± 10 % mcg, 55 ± 10 % mcg or 60 ± 10 % mcg of dexmedetomidine or its pharmaceutically acceptable salt, whereby dexmedetomidine or its pharmaceutically acceptable salt creates C_plasma 0.1 ± 10 % ng/ml ranging from 15 ± 10 % minutes to 20 ± 10 % minutes after administration and has an analgesic effect for an hour immediately after administration of dexmedetomidine or a pharmaceutically acceptable salt thereof. At that, adult is ready for cooperation, is oriented and calm for an hour immediately after administration of dexmedetomidine or its pharmaceutically acceptable salt.

EFFECT: method enables treating the pain without considerable sedative action.

10 cl, 2 dwg, 13 tbl, 6 ex