SELECTING AGENTS MODULATING GASTROINTESTINAL PAIN Russian patent published in 2019 - IPC A61K35/747 A61K35/74 G01N33/68 A61P1/00 

Abstract RU 2692671 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the pharmaceutical industry, specifically to a method of selecting a lactic acid bacteria strain for use in reducing or preventing gastrointestinal pain in a human. Method of selecting a lactic acid bacteria strain for use in reducing or preventing gastrointestinal pain in a human, wherein said method involves: selection of lactic acid bacteria strain capable to reduce spontaneous and/or induced activation of transient receptor potential on vaniloid 1, TRPV1, or a conditioned medium from said lactic acid bacteria strain, capable of reducing spontaneous and/or induced activation of TRPV1. Application of a strain of lactic acid bacteria or conditioned medium from said strain of lactic acid bacteria. Use of the composition.

EFFECT: above-described group of inventions enables reducing or preventing gastrointestinal pain in humans.

13 cl, 7 dwg, 2 ex

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RU 2 692 671 C2

Authors

Konolli Imonn

Kuntse Volfgang

Binenshtok Dzhon

Dates

2019-06-26Published

2015-01-23Filed