METHOD FOR LIQUID-PHASE SYNTHESIS OF H-INP-(D)BAL-(D)TRP-PHE-APC-NH AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 2019 - IPC C07K1/02 C07K7/06 C07K14/60 C07K5/97 C07K5/78 C07K5/65

Abstract RU 2694051 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method for liquid phase synthesis of the ghrelin analogue H-Inp-(D)Bal-(D)Trp-Phe-Apc-NH₂ (SEQ ID NO: 1, formula (I)) and pharmaceutically acceptable salts thereof.

EFFECT: industrial scale enables to obtain an analogue of ghrelin SEQ ID NO: 1 and provides high purity.

18 cl, 24 dwg, 1 ex

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RU 2 694 051 C2

Authors

Decroos, Karel

Titeux, Olivier

Dates

2019-07-09—Published

2015-03-04—Filed