FIELD: organic chemistry, amino acids.
SUBSTANCE: invention claims new compounds that elicit both high affinity and selectivity with respect to neuromedin B and somatostatin receptors. Compounds has the following formula: 
wherein α-atom in each group among AA1, AA2, AA3, AA4, AA5, AA6, AA7 and AA8 is substituted optionally and independently with (C1-4)-alkyl-(C3-4)-alkenyl, (C3-4)-alkynyl or (C1-6))-alkyl-C(O)-; AA1 is absent or means Ac-D-Phe or D- or L-isomer of R11, Pip, Pro or aromatic α-amino acid taken among the group consisting of Cpa, Dip, Nal and Phe; AA2 is absent or means Pal, Phe, Tyr; AA3 means D- or L-isomer of Cys; AA4 means D- or L-isomer of Trp; AA5 means Lys; AA6 means D- or L-isomer of Cys; AA7 is absent or means A3c, A4c, A5c, A6c, Abu, Aic, β-Ala, Gaba, Nle, Pro, Sar, Thr, Thr(Bzl) or Val; AA8 is absent or means R11, Nal, Thr, Tyr, Phe or Nle; each among R1 and R2 represents independently hydrogen atom (H) or absent; R5 means -NH2,; R11 means D- or L-amino acid independently in each case and AA3 and AA6 are bound by disulfide bond.
EFFECT: valuable biological properties of compounds.
9 cl, 2 tbl, 1 ex
