FIELD: pharmaceuticals.
SUBSTANCE: invention relates to a new tryptane amine derivative of formula 1
.
Compound has high anticancer activity, increases therapeutic activity of anti-tumor antibiotics, and exhibits anti-inflammatory and antimicrobial properties.
EFFECT: as compared to triptanetrin compound is soluble in water, pharmacologically acceptable aqueous media and biological fluids, which promotes its use in form of aqueous solutions; much less toxic, which increases safety and effectiveness of its therapeutic use; wherein the compound reduces the immunosuppressive effect, and the higher anticancer potential of compound (1) enables to substantially increase the effectiveness of using it in treating oncological diseases.
1 cl, 1 dwg, 4 tbl, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| GEL COMPOSITION OF WOUND HEALING, BURNTREATING, ANTIINFLAMMATORY, HEPATOPROTECTIVE, ANTIDIABETIC AND ANTINEOPLASTIC ACTION | 2008 |
|
RU2366408C1 |
| PHARMACEUTICAL COMPOSITION POSSESSING THERAPEUTIC ACTION ON VARIOUS SKIN PATHOLOGIES | 2014 |
|
RU2549475C1 |
| ANTI-INFLAMMATORY MEDICATION WITH ANTICOAGULANT, ANTITUMOUR AND ANTIMETASTETIC ACTIVITY | 2009 |
|
RU2412712C1 |
| ANTI-INFLAMMATORY AND ANTINEOPLASTIC ANTICOAGULANT | 2009 |
|
RU2408379C2 |
| ANTI-TUMOR NAPHTHOINDOLE-3-CARBOXAMIDE DERIVATIVE | 2019 |
|
RU2712191C1 |
| INDOL-3-CARBOXIC ACID DERIVATIVES WITH ANTI-TUMOR ACTIVITY | 2022 |
|
RU2782931C2 |
| ANTITUMOR CHEMICAL PREPARATION | 2016 |
|
RU2629608C1 |
| METHOD FOR POTENTIATING ACTIVITY OF ANTI-TUMOUR CYTOTOXIC PREPARATIONS | 2017 |
|
RU2714140C2 |
| ANTITUMOUR ANTHRAFURANDIONE AND BASED PHARMACEUTICAL COMPOSITIONS | 2014 |
|
RU2554939C1 |
| AGENT "LIZOLAKT" POTENTIATING ANTITUMOR ACTIVITY OF CYTOTOXIC PREPARATIONS | 2006 |
|
RU2311196C1 |
