FIELD: chemistry.
SUBSTANCE: invention relates to a novel compound – (S)-3-(3-aminopyrrolidine-1-carbonyl)-4,11-dihydroxy-2-methylnaphtho[2,3-ƒ]indole-5,10-dione and its pharmaceutically acceptable salt. (S)-3-(3-aminopyrrolidine-1-carbonyl)-4,11-dihydroxy-2-methylnaphtho[2,3-ƒ]indole-5,10-dione corresponds to formula
EFFECT: compounds have anti-tumor activity and can be used for treating oncological diseases, for example, various types of leukemia.
1 cl, 3 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW HETEROARENANTHRACENE-2-CARBOXAMIDE DERIVATIVES INHIBITING TUMOUR GROWTH | 2016 |
|
RU2631100C1 |
| ANTITUMOUR ANTHRAFURANDIONE AND BASED PHARMACEUTICAL COMPOSITIONS | 2014 |
|
RU2554939C1 |
| CYTOTOXIC LINEAR HETEROCYCLIC DERIVATIVES OF ANTHRACENEDIONE HAVING IN SIDE CHAIN CYCLIC DIAMINES, ACTIVE TOWARDS TUMOUR CELLS WITH MULTIDRUG RESISTANCE | 2009 |
|
RU2412166C1 |
| ORAL ANTITUMOUR DRUGS AND METHOD FOR ONCOLOGICAL DISEASES TREATMENT | 2016 |
|
RU2639479C1 |
| MULTITARGET INHIBITORS OF TUMOUR GROWTH BASED ON LINEAR HETEROARENE ANTHRACENEDIONES | 2013 |
|
RU2527273C1 |
| DERIVATIVE OF THE CLASS OF N-GLYCOSIDES INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOLE-5,7-DIONE - N-{12-(β-D-XYLOPYRANOSYL)-5,7-DIOXO-INDOLO[2,3-A]PYRROLO[3,4-C]CARBAZOL-6-YL} PYRIDINE-2-CARBOXAMIDE, WHICH HAS CYTOTOXIC AND ANTITUMOR ACTIVITY | 2017 |
|
RU2667906C1 |
| ANTICANCER PHARMACEUTICAL COMPOSITIONS AND METHOD OF TREATING BREAST CANCER | 2015 |
|
RU2581022C1 |
| TUMOUR THERAPY AGENT | 2019 |
|
RU2726801C1 |
| N-GLYCOSIDES OF INDOLO[2,3-a]PYRROLO[3,4-c]CARBAZOLES HAVING ANTITUMOUR ACTIVITY | 2014 |
|
RU2548045C1 |
| ANTITUMOUR AGENT | 2014 |
|
RU2572691C1 |
