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2 408 379

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(51)

IPC

A61K31/727(2006-01-01)

A61P7/02(2006-01-01)

A61P29/00(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2009107800/15, 2009-03-04

(24)

Start date

2009-03-04

(22)

Actual filing date

2009-03-04

(45)

Published

2011-01-10

(72)

Inventor

Tolstikova Tat'Jana GenrikhovnaSorokina Irina Vasil'EvnaZhukova Natal'Ja Anatol'EvnaBaev Dmitrij SergeevichPonedel'Kina Irina Jur'EvnaLukina Elena SergeevnaKhajbrakhmanova Ehl'Vira AzamatovnaOdinokov Viktor NikolaevichDzhemilev Usein Memetovich

(73)

Holder

Uchrezhdenie Rossijskoj Akademii Nauk Institut Neftekhimii I Kataliza Ran

ANTI-INFLAMMATORY AND ANTINEOPLASTIC ANTICOAGULANT Russian patent published in 2011 - IPC A61K31/727 A61P7/02 A61P29/00 A61P35/00

Abstract RU 2408379 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: there is offered the administration of heparin conjugated with 2-aminoethanesulfonic acid (taurine) of formula (1), synthesised with a condensing reagent - water-soluble 1-ethyl-3[3 (dimethylamino)propyl]carbodiimide as an anti-inflammatory and antineoplastic anticoagulant.

EFFECT: compound surpasses heparin in anticoagulating ability, has high anti-inflammatory activity, while antineoplastic activity is comparable with the effect of antineoplastic preparations (doxorubicin, cyclophosphan, vincristine).

5 tbl, 4 ex

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RU 2 408 379 C2

Authors

Tolstikova Tat'Jana Genrikhovna

Sorokina Irina Vasil'Evna

Zhukova Natal'Ja Anatol'Evna

Baev Dmitrij Sergeevich

Ponedel'Kina Irina Jur'Evna

Lukina Elena Sergeevna

Khajbrakhmanova Ehl'Vira Azamatovna

Odinokov Viktor Nikolaevich

Dzhemilev Usein Memetovich

Dates

2011-01-10—Published

2009-03-04—Filed