AGENT HAVING NOOTROPIC EFFECT ON BODY Russian patent published in 2019 - IPC A61K38/12 A61P25/28 A61K47/26 A61K9/20 

Abstract RU 2694233 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to preparations of peptidic origin, having nootropic action. Disclosed agent is an oral dosage form and contains cyclo (prolyl-alanine) in amount of 4–10 wt. % immobilized on a sorbent which is D-mannitol and excipients. Composition enables to obtain a granular or tablet dosage form when adding auxiliary substances. Implementation of the invention enables to obtain an agent providing a bioavailability coefficient of cyclo (prolyl-alanine) with intragastric introduction to 0.88±10.05, that is approximately 90 % of the preparation introduced peros falls into the bloodstream.

EFFECT: with oral administration of the declared agent, evident protoprotective activity is observed, preservation of the memorable trace in healthy individuals and individuals with ischemic cerebral involvement is increased, which makes the preparation promising for treating cognitive brain injuries and similar diseases.

5 cl, 3 tbl, 9 ex

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RU 2 694 233 C2

Authors

Kolobov Aleksandr Aleksandrovich

Smirnova Mariya Pavlovna

Stefanenko Lyudmila Ivanovna

Shpen Vladimir Mikhajlovich

Dates

2019-07-10Published

2017-10-13Filed