FIELD: medicine; pharmaceuticals.
SUBSTANCE: present invention refers to pharmaceutical chemistry and drug therapy and particularly concerns a compound of formula (I), a method of producing and using it as a negative allosteric modulator of metabotropic glutamate receptor (mGluR5, subtype 5).
EFFECT: disclosed is 5-aromatic alkynyl-substituted benzamide compound and a method for production thereof, a pharmaceutical composition and use thereof.
9 cl, 2 dwg, 8 tbl, 85 ex
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