VAGINAL SUPPOSITORY FOR TREATING INFECTIOUS-INFLAMMATORY VAGINAL DISEASES, AND A METHOD FOR PREPARING Russian patent published in 2019 - IPC A61K9/02 A61K33/22 A61K47/14 A61K47/26 A61P15/02 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to medicine and pharmaceutics, namely to a vaginal suppository for treating infectious-inflammatory diseases of the vulva and vagina, particularly vulvar and vaginal diseases caused by Candida fungi, for example, vaginal and vulvovaginal candidiasis, where said vaginal suppository containing an active ingredient – sodium tetraborate, dispersed in the base – fat, which is solid at room temperature, which is a mixture of triglycerides, diglycerides and medium-chain (C₁₆-C₁₈) monoglycerides of fatty acids with hydroxyl number of 40 to 50 mg KOH/g, as well as an emulsifier – polyoxyethylene (20) sorbitan monooleate and an additive preventing melting temperature reduction and time of complete suppository deformation – distilled monoglycerides, and to a method of such suppository manufacturing.

EFFECT: providing a convenient, safe in use and storage stable dosage form of sodium tetraborate providing in its medical application uniform distribution of the drug on the vaginal mucosa.

13 cl, 5 ex, 4 tbl, 1 dwg