HUMANISED HUMAN CD19 ANTIBODIES AND METHODS FOR USE THEREOF Russian patent published in 2020 - IPC C07K16/28 A61K39/395 A61P35/00 A61P37/00 

Abstract RU 2731156 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to an antibody which specifically binds to human CD19, as well as to a pharmaceutical composition containing it. Also disclosed is use of said antibody in preparing a drug for CD19 binding. Invention also relates to a method for B-cell population depletion involving using said antibody.

EFFECT: invention enables effective treatment of a patient suffering from a disease associated with a pathological increase in the number of B-cells.

13 cl, 8 ex

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RU 2 731 156 C1

Authors

Zhorzh Gi

Messner Ekkekhard

Lariver Loran

Khaas Aleksandr

Kettenberger Gubert

Ferrara Koller Klaudia

Shlotauer Tilman

Molkhoj Mikhel

Dates

2020-08-31Published

2016-09-30Filed