FIELD: biotechnology.
SUBSTANCE: invention relates to a live attenuated recombinant knockout mutant of nodular dermatitis virus, where the gene of interleukin-10-like protein or functional part of said gene is inactivated in viral genome. This invention specifically relates to a recombinant knockout mutant of cattle nodular dermatitis virus, to pharmaceutical compositions containing this knockout mutant, to methods of obtaining this knockout mutant and to application of this knockout mutant.
EFFECT: invention increases efficiency of protecting animals from a disease caused by virus from the viral genus Capripoxvirinae.
15 cl, 14 dwg, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREVENTING NODULAR DERMATITIS IN BOVINE ANIMALS | 2017 |
|
RU2659212C1 |
| STRAIN "VNIIZZH 2003" OF GOAT-POX VIRUS VARIOLA VIRUS CAPRINUM TO PRODUCE BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PROPHYLACTICS OF GOAT-POX | 2008 |
|
RU2389791C1 |
| FMDV VACCINES BASED ON A RECOMBINANT ADENOVIRAL VECTOR AND USE THEREOF | 2017 |
|
RU2725495C2 |
| IMMUNOLOGICAL COMPOSITION | 2009 |
|
RU2506094C2 |
| STRAIN OF COW HERPES VIRUS TYPE-I (BHV-I) CNCM N 1-1213, VACCINE, DIAGNOSTIC SEROLOGICAL REAGENT, METHOD OF VACCINATION, METHOD OF SEROLOGICAL DISTINCTION | 1992 |
|
RU2170254C2 |
| STRAIN "PRIVOLZHSKY" OF A VIRUS OF NODULAR DERMATITIS IN CATTLE DERMATITIS NODULARIS BOVUM, A GENUS CAPRIPOXVIRUS FOR MANUFACTURING BIOPREPARATIONS FOR DIAGNOSTICS AND SPECIFIC PREVENTION OF INFECTIOUS DERMATITIS OF BOVINE ANIMALS | 2019 |
|
RU2708335C1 |
| STRAIN OF NODULAR DERMATITIS VIRUS OF CATTLE DERMATITIS NODULARIS BOVUM, GENUS CAPRIPOXVIRUS TO PRODUCE BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF NODULAR DERMATITIS OF CATTLE | 2016 |
|
RU2606254C1 |
| PRODUCING POULTRY AND OTHER ANIMALS RESISTANT TO VIRAL DISEASES | 2006 |
|
RU2533804C2 |
| "KALMYKIA-16" STRAIN OF SHEEP POX VIRUS FOR VIROLOGICAL, MOLECULAR-GENETIC, MONITORING STUDIES, PRODUCTION OF VACCINES AND DIAGNOSTIC PREPARATIONS | 2016 |
|
RU2647768C1 |
| VIRUS-VACCINE ASSOCIATED AGAINST SHEEP POX AND GOAT POX CULTURE DRY | 2009 |
|
RU2403064C1 |
