PHARMACEUTICAL COMPOSITION BASED ON BIS-(N-MONOSUCCINYL-L-SERYL-L-LYSINE) HEXAMETHYLENEDIAMIDE (GSB-106) Russian patent published in 2019 - IPC A61K38/05 A61K47/00 A61K9/20 A61K9/48 A61P25/24 A61P25/28 

Abstract RU 2697254 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to pharmacy, and concerns a pharmaceutical composition containing a dimeric dipeptide mimetic BDNF - hexamethylene diamide bis-(N-monosuccinyl-L-seryl-L-lysine) (GSS-106) and as additives - filler, binder and glidant, in amounts specified in claims. Preferably, the filler used is a mixture of lactose and microcrystalline cellulose with particle size of 101 in ratio of 2:1, respectively, as a binder, a copolymer of polyvinyl alcohol and polyethylene glycol, as a sliding substance - magnesium stearate. Pharmaceutical composition is intended for forming tablets and filling capsules.

EFFECT: pharmaceutical composition under the invention extends the range of products with antidepressant activity in a solid dosage form and meets all requirements of GF XIII.

3 cl, 4 tbl, 4 ex

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RU 2 697 254 C1

Authors

Seredenin Sergej Borisovich

Gudasheva Tatyana Aleksandrovna

Alekseev Konstantin Viktorovich

Blynskaya Evgeniya Viktorovna

Bueva Viktoriya Vladimirovna

Garibova Taisiya Leonovna

Povarnina Polina Yurevna

Minaev Sergej Viktorovich

Dates

2019-08-13Published

2018-02-28Filed