FIELD: biotechnology; medicine.
SUBSTANCE: present invention relates to biotechnology, specifically to novel peptides which inhibit NADPH-oxidase 1 (Nox1), and can be used in medicine for preventing or treating pathological conditions and diseases associated with increased production of Nox1 active forms of oxygen (ROS), including cancer, atherosclerosis, angiogenesis and premature aging. Peptides, as well as compositions containing them, are also effective in treatment, recovery and protection of skin, mucous membrane, scalp and/or hair from UV radiation, UV-damage, UV-aging or for increasing photoprotection from both UV-A and UV-B irradiation.
EFFECT: invention enables to obtain peptides which are able to selectively reduce or inhibit Nox1 activity.
22 cl, 12 dwg, 11 tbl, 8 ex
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