METHOD OF ACUTE PANCREATITIS CORRECTION IN RATS USING MONTMORILLONITE-BASED ENTEROSORBENT Russian patent published in 2019 - IPC A61K33/06 A61P1/18 

Abstract RU 2700920 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to experimental pharmacology, and can be used for correction of acute pancreatitis in rats using montmorillonite-based enterosorbent. That is ensured by simulating acute pancreatitis by intraperitoneal single administration of a solution of L-arginine in a phosphate buffer pH = 6.8 in dose of 1.5 g/kg. That is followed by correcting acute pancreatitis by intragastric introduction of an enterosorbent based on montmorillonite. Montmorillonite-based enterosorbent is activated with hydrochloric acid and contains montmorillonite 62.1 wt%; silver 0.11 wt%; organic additives: dextrose, vanillin, saccharine 37.79 wt%.

EFFECT: invention reduces blood serum amylase activity.

1 cl, 2 tbl

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Authors

Tarykin Dmitrij Nikiforovich

Pokrovskij Mikhail Vladimirovich

Chuev Vladimir Petrovich

Buzov Andrej Anatolevich

Peresypkina Anna Aleksandrovna

Ryndina Tatyana Vladimirovna

Kazakova Valentina Sergeevna

Vezentsev Aleksandr Ivanovich

Peristaya Lidiya Fedotovna

Peristyj Vladimir Aleksandrovich

Bukhanov Vladimir Dmitrievich

Mikhajlyukova Mariya Olegovna

Korokin Mikhail Viktorovich

Tishin Anton Nikolaevich

Dates

2019-09-24Published

2018-11-30Filed