FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmaceutical industry, and concerns a composition having a complex effect on the vascular endothelium. The composition contains L-arginine or L-citrulline, and an arginase inhibitor in a solid dosage form. The composition possess an endothelial protective, vasodilating and angioprotective effect. The synergetic effect is provided by combining NO donators and the arginase inhibitors in the retard form.
EFFECT: preparing the composition possessing the complex effect on the vascular endothelium.
7 cl, 5 ex, 54 tbl, 2 dwg
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Authors
Dates
2012-10-20—Published
2011-05-31—Filed