FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and can be used for treating or slowing progression of cancer in an individual. That is ensured by administering an effective amount of an antagonist of an anti-PD-L1 antibody, or an antigen-binding fragment thereof and an anti-TIGIT antibody antagonist, or an antigen-binding fragment thereof. Also disclosed is a method for reducing or inhibiting recurrence of cancer in an individual.
EFFECT: group of inventions provides reducing tumour growth and inducing tumour elimination by synergetic action of antagonists of anti-PD-L1-antibody and anti-TIGIT-antibody.
16 cl, 37 dwg, 14 ex
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| ANTI-PD-L1 ANTIBODIES AND METHODS FOR THEIR DIAGNOSTIC USE | 2015 |
|
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|
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| METHODS OF TREATING CANCER USING PD-1 AXIS BINDING AND VEGF ANTAGONISTS | 2013 |
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