MALARIA VACCINES Russian patent published in 2019 - IPC A61K39/15 C07K19/00 C12N15/09 

FIELD: biotechnology.

SUBSTANCE: invention refers to biotechnology and molecular biology. Presented is a virus-like particle for vaccination against malaria, which contains a structural virus polypeptide derived from Chikungunya virus (CHIKV) or Venezuelan horse encephalitis virus (VEEV), and at least one malaria antigen, wherein said structural virus polypeptide comprises at least one first attachment region in the envelope protein and said at least one malaria antigen comprises at least one second attachment site, said malaria antigen is an antigen containing (NPNA)_n, where n ranges from 4 to 30, and/or the antigen contains (EYLNKIQNSLSTEWSPCSVT)_y, where y ranges from 1 to 6, and said structural virus polypeptide and said malaria antigen are bound by said at least one first and said at least one second attachment portions.

EFFECT: invention can be used in medicine for malaria control.

12 cl, 11 dwg, 4 tbl, 7 ex