FIELD: biotechnology.
SUBSTANCE: invention relates to the biotechnology. Described is a virus-like particle for inducing and/or enhancing an immune response against antigen in mammals, comprising a structural virus polypeptide and at least one antigen, wherein the viral structural polypeptide comprises at least one first attachment site, at least one antigen comprises at least one second attachment site, structural virus polypeptide and antigen are connected through at least one first and at least one second attachment site, and the viral structural polypeptide is derived from Chikungunya virus (CHIKV) or Venezuelan equine encephalitis virus (VEEV), in which the antigen does not originate from CHIKV virus or VEEV virus.
EFFECT: invention extends the range of immunological agents.
9 cl, 11 dwg, 1 tbl, 7 ex
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