POLYPEPTIDE FOR INHIBITING MIGRATION AND INVASION OF SQUAMOUS CELL CARCINOMA OF THE ORAL CAVITY Russian patent published in 2019 - IPC A61K38/16 

Abstract RU 2705547 C1

FIELD: biotechnology.

SUBSTANCE: invention refers to biotechnology, medicine and molecular biopharmacology. Disclosed is use of a polypeptide having an amino acid sequence corresponding to SEQ ID NO:1 to suppress viability, migration and invasion of squamous cell carcinoma of the oral cavity, reducing expression of oncogenes ITGAV, BCL2 and MMP7.

EFFECT: use of the invention provides higher anticancer efficacy of endostatin protein with respect to squamous cell carcinoma of the oral cavity.

1 cl, 7 dwg

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RU 2 705 547 C1

Authors

Yang Baofeng

Bai Yunlong

Yan Baofen

Baj Yunlong

Dates

2019-11-07Published

2018-10-26Filed