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(19)

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2 735 102

(13)

(51)

IPC

C07K16/30(2006-01-01)

G01N33/574(2006-01-01)

A61K39/00(2006-01-01)

(21) (22)

Application

2019113308, 2017-08-16

(24)

Start date

2017-08-16

(22)

Actual filing date

2017-08-16

(45)

Published

2020-10-28

(72)

Inventor

Koh Sang SeokKim Yeon JeongYoun So EunKim Song CheolHong Seung-MoJeong Seong Yun

(73)

Holder

Dong-A University Research Foundation For Industry-Academy CooperationPrestige Biopharma Pte. Ltd.

ANTIBODY SPECIFICALLY BINDING TO PAUF PROTEIN, AND ITS USE Russian patent published in 2020 - IPC C07K16/30 G01N33/574 A61K39/00

Abstract RU 2735102 C1

FIELD: biochemistry.

SUBSTANCE: invention relates to an antibody which binds to an activating factor protein of pancreatic adenocarcinoma (PAUF). Also disclosed is a polynucleotide encoding said antibody; an expression vector and a transformant containing said polynucleotide; pharmaceutical composition, conjugate, kit containing said antibody. What is disclosed are methods for preventing or treating cancer, inhibiting proliferation, migration or invasion of cancer cells, diagnosing cancer and screening with said antibody.

EFFECT: invention is capable to effectively treat cancer diseases, where cancer is pancreatic cancer or ovarian cancer.

14 cl, 16 dwg, 3 tbl, 3 ex

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RU 2 735 102 C1

Authors

Koh Sang Seok

Kim Yeon Jeong

Youn So Eun

Kim Song Cheol

Hong Seung-Mo

Jeong Seong Yun

Dates

2020-10-28—Published

2017-08-16—Filed