ANTIBODIES BINDING IL-4 AND/OR IL-13, AND USE THEREOF Russian patent published in 2019 - IPC C07K16/18 C07K16/24 A61K39/395 

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. Described is a group of inventions comprising an isolated humanised antibody or fragment thereof, which specifically binds IL-13 (embodiments), a pharmaceutical composition for treating a disease, associated with IL-13, use of a therapeutically effective amount of the antibody or a fragment thereof for preparing a medicament for treating a IL-13 related disease, use of the antibody or fragment thereof for preparing a medicament for treating, suppressing or preventing an IL-13 related disease in a mammal, use of the antibody or a fragment thereof for preparing a drug which is used to suppress a TH-2 mediated response, use of the antibody or a fragment thereof to suppress a TH-2 mediated response, an isolated nucleic acid molecule, an expression vector, an isolated host cell for producing said antibody or a fragment thereof. In one embodiment, the antibody is a bispecific antibody and binds to IL-13 and IL-4.

EFFECT: invention extends the arsenal of antibodies binding to IL-13.

21 cl, 2 dwg, 8 tbl, 8 ex