COMBINATION OF ONCOLYTIC VIRUS WITH MODULATORS OF IMMUNOLOGICAL CONTROL POINTS Russian patent published in 2019 - IPC C12N7/00 A61K35/76 A61K39/00 C07K14/475 C12N15/863 A61K35/768 

Abstract RU 2705780 C2

FIELD: medicine.

SUBSTANCE: present invention provides a combination comprising at least oncolytic virus and one or more immunological control point modulators for use in treating a proliferative disease, such as cancer. It also refers to a kit containing said oncolytic virus and said one or more immunological control point modulators in separate containers. It also refers to a pharmaceutical composition containing an effective amount of said oncolytic virus and said one or more immunological control point modulators.

EFFECT: disclosed is a combination of oncolytic virus with modulators of immunological control points.

21 cl, 7 dwg, 1 tbl

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RU 2 705 780 C2

Authors

Tsitfogel Lorans

Previll Ksave

Fend Letitsiya

Dates

2019-11-11Published

2015-07-16Filed