GLA DOMAINS AS THERAPEUTIC AGENTS Russian patent published in 2019 - IPC C07K16/00 A61P35/00 A61P37/00 A61P31/12 A61P7/02 A61P31/00 

Abstract RU 2705786 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the biotechnology. Described is a polypeptide for targeting the released phosphatidylserine (PtdS) of a cell membrane, which involves: (a) protein S gamma-carboxyglutamic acid domain presented in SEQ ID NO: 1, or a sequence which is at least 95 % homologous to it, which does not contain a protease domain or a hormone-binding domain; and (b) S EGF domain protein.

EFFECT: invention can be used for treating cancer, viral disease, autoimmune disease, hypercoagulation disorder, sepsis, vascular-occlusive crisis.

26 cl, 8 dwg, 1 ex

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RU 2 705 786 C2

Authors

Bozon Maksin

Khermiston Terri

Dates

2019-11-11Published

2014-03-13Filed